Drug Uses
Effexor XR is a potent
inhibitor of the reuptake of
serotonin and norepinephrine-two
neurotransmitters thought to
play important roles in the
pathophysiology of
depression. Correcting the
imbalance of these two
chemicals may help relieve
symptoms of depression.
How Taken
Effexor XR comes as a
tablet to take by mouth. It
is usually taken two or
three times a day and should
be taken with food. Each
capsule should be swallowed
whole with fluid and not
divided, crushed, chewed, or
placed in water, or it may
be administered by carefully
opening the capsule and
sprinkling the entire
contents on a spoonful of
applesauce. This drug/food
mixture should be swallowed
immediately without chewing
and followed with a glass of
water to ensure complete
swallowing of the pellets.
Warnings/Precautions
Before starting Effexor
XR, tell your doctor about
any medicines you're taking,
including over-the-counter
drugs and herbal
supplements. People taking
MAOIs should not take
Effexor XR. Patients taking
antidepressants should be
watched closely for signs
that their condition is
getting worse or that they
are becoming suicidal,
especially when they first
start therapy, or when their
dose is increased or
decreased. Patients should
also be watched for becoming
agitated, irritable,
hostile, impulsive, or
restless. Such symptoms
should be reported to the
patient’s doctor right away.
Effexor XR may raise blood
pressure in some patients,
so blood pressure should be
monitored regularly. When
people suddenly stop using
or quickly lower their daily
dose of Effexor XR,
discontinuation symptoms may
occur. Talk to your doctor
before discontinuing or
reducing your dose of
Effexor XR. Pregnant or
nursing women shouldn’t take
any antidepressant without
consulting their doctor.
Until you see how Effexor XR
affects you, be careful
doing such activities as
driving a car or operating
machinery. Avoid drinking
alcohol while taking Effexor
XR.
Missed Dose
Take the missed dose as
soon as you remember.
However, if it is almost
time for the next dose, skip
the missed dose and take
only the next one as
directed. Do not take a
double dose of this
medication.
Possible Side Effects
If you experience any of
the following serious side
effects, stop taking Effexor
XR and contact your doctor
immediately or seek
emergency medical treatment:
an allergic reaction
(difficulty breathing;
closing of the throat;
swelling of the lips,
tongue, or face; or hives);
seizures; or an irregular
heartbeat or severely high
blood pressure (blurred
vision, headache). Other,
less serious side effects
may be more likely to occur.
Continue to take Effexor XR
and talk to your doctor if
you experience nausea,
vomiting, upset stomach,
abdominal pain, or loss of
appetite or weight; dry
mouth; drowsiness or
dizziness; mild tremor,
anxiety, or agitation;
insomnia; abnormal dreams;
sexual problems such as
impotence, abnormal
ejaculation, difficulty
reaching orgasm, or
decreased libido; sweating;
yawning; or increase in
blood cholesterol levels
(detected by blood tests);
Side effects other than
those listed here may also
occur. Talk to your doctor
about any side effect that
seems unusual or that is
especially bothersome.
Storage
Store Effexor XR at room
temperature (68F to 77F or
20C to 25C). Keep Effexor XR
away from children.
Overdose
Seek emergency medical
attention if an overdose is
suspected. Symptoms of an
Effexor XR overdose may
include dizziness,
drowsiness, numbness,
nausea, irregular
heartbeats, seizures, and
unconsciousness.
More Information
Use caution when driving,
operating machinery, or
performing other hazardous
activities. Effexor XR may
cause dizziness or
drowsiness. If you
experience dizziness or
drowsiness, avoid these
activities. Use alcohol
cautiously. Alcohol may
increase drowsiness,
dizziness, and confusion Do
not stop taking Effexor XR
without first talking to
your doctor. Your doctor may
need to gradually reduce the
dose before stopping the
medication completely.
Stopping the medication
suddenly may cause
unpleasant side effects to
occur.
Disclaimer
This drug information is
for your information
purposes only, it is not
intended that this
information covers all uses,
directions, drug
interactions, precautions,
or adverse effects of your
medication. This is only
general information, and
should not be relied on for
any purpose. It should not
be construed as containing
specific instructions for
any particular patient.
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